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Placebo, Parkinson's, Pain and PET: a neuroimaging perspective.
Thursday, March 24, 2011 from 4:30 PM to 6:30 PM (PDT)
Vancouver, British Columbia
* Please note: the lecture begins at 5 pm. 430-450 pm is pre-talk time to socialize, have wine and cheese, and choose your seat. An introduction to the lecture will begin at 450 pm. *
The "placebo effect" refers to a perceived or actual improvement in a medical condition after a patient has received a sham or simulated medical intervention. The Latin word "placebo" means "I will please", and originally referred to a medicine created more to please than to benefit the patient.
Dr. Stoessl and his colleagues were the first to show that people experiencing the placebo effect have specific changes in their brain activity. They studied the brain's uptake of dopamine during activation of the placebo effect, using PET, Positron Emission Tomography, imaging. The results of the research were published in the Lancet Neurology, 2002, among other journals, including Science, and Biological Psychiatry.
Dr. Jon Stoessl is a highly recognized expert in the area of neuroimaging of Parkinson's Disease. He is the Director the Pacific Parkinson's Research Centre, which conducts the largest peer-reviewed Parkinson's research program in Canada. Also, he is the Canadian Research Chair for Parkinson's Disease, the Director of the National Centre for Excellence for Parkinson's Disease, the Head of Neurology at UBC, and has been awarded the Order of Canada for his contribution.
Archives of General Psychiatry: Effects of expectation on placebo-induced dopamine release in Parkinson disease.
Lancet Neurology: The placebo effect in neurological disorders.
Molecular Imaging and Biology: Understanding the placebo effect: contributions from neuroimaging
Reuters Health: Brain's Reward System helps drive placebo effect
Scientific American Mind: Placebo Effect: A Cure in the Mind
The Paetzold Lecture Theatre is located in Vancouver General Hospital, 890 West 12th Avenue, Vancouver B.C. V5Z 1M9. From the main hospital entrance on 12th Ave, entering through the second floor door that says "Jim Pattison Pavilion" above the door, go past the Cafe Ami, then go around the info desk, continue straight down the hall, until you are facing the Cordula & Günter Paetzold HEC sign – continue to the left of this large sign, and you will find the main entrance through double doors on your right (just past the elevators), and then will find yourself in the atrium area for the lecture theatre.
The atrium will be where people can socialize from 430 to 450 pm, with light refreshments. The lecture and discussion will take place in the lecture theatre adjacent to this atrium.